منابع مشابه
An Unresolved Issue
A large body of evidence suggests that aldosterone excess is a common cause of hypertension with a prevalence of primary aldosteronism (PA) of 10% in patients with mildto-moderate hypertension and 20% in patients with resistant hypertension.1 Experimental and clinical data also demonstrate that aldosterone excess contributes importantly to the development and progression of cardiorenal disease....
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Premature birth is the world's leading cause of neonatal mortality with worldwide estimates indicating 11.1% of all live births were preterm in 2010. Preterm birth rates are increasing in most countries with continual differences in survival rates amongst rich and poor countries. Preterm birth is currently an important unresolved global issue with research efforts focusing on uterine quiescence...
متن کاملTRPA1 and Cold Transduction: An Unresolved Issue?
TRPA1 was originally characterized as a cold-activated ion channel; however, since the initial description there has been some disagreement about its role in cold sensation. Here, we review the literature on the function of TRPA1 as a cold sensor. Many studies have demonstrated that TRPA1 can be activated by cold when expressed in heterologous systems, but its role as a cold sensor in native pe...
متن کاملCorrecting tricuspid regurgitation: an unresolved issue.
Tricuspid valve (TV) dysfunction is common in patients with other diseased valves and heart conditions. Tricuspid regurgitation (TR) is often found in patients with left-sided valve disease, especially when there is pulmonary hypertension. Over 30% of candidates for mitral valve surgery have moderate or severe TR. In most cases there is a functional component, due to the remodeling of the right...
متن کاملWeight change and incident diabetes: addressing an unresolved issue.
The impact of weight change on diabetes incidence remains unclear. To clarify the role of weight change as a risk factor for diabetes, the authors assessed the association between weight change and diabetes incidence conditional upon either initial or attained body mass index (BMI). They used 7,837 observations available from repeated measurements of 4,259 participants (men and women aged 20-59...
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ژورنال
عنوان ژورنال: Internal Medicine: Open Access
سال: 2015
ISSN: 2165-8048
DOI: 10.4172/2165-8048.1000192